Dengue IgG Antibody - ELISA

Also Know as: Dengue Virus IgG, Immunoassay

1998

Last Updated 1 November 2024

What is Dengue IgG Antibody - ELISA

The Dengue IgG antibodies ELISA test is a procedure used in medical laboratories to diagnose Dengue fever. Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. The following points explain the procedure and its importance:

  • Definition: The Dengue IgG Antibody - ELISA is a blood test that detects the presence of Dengue IgG antibodies in the blood. IgG is an antibody that the body produces in response to a dengue infection.
  • Purpose: The main purpose of the Dengue IgG Antibody - ELISA test is to determine whether a person has been infected with the dengue virus. A positive result indicates a past or recent infection.
  • Procedure: The ELISA (Enzyme-Linked Immunosorbent Assay) technique is used in this test. It involves taking a blood sample from the patient, which is then placed on a specially treated plate. If Dengue IgG antibodies are present in the sample, they will bind to these plates.
  • Significance: The ELISA test is a crucial diagnostic tool for Dengue fever. Its high sensitivity and specificity make it a reliable method for the detection of Dengue IgG antibodies. It helps in the accurate diagnosis and management of Dengue fever.
  • Limitations: While the Dengue IgG antibodies ELISA test is highly effective, it's not without limitations. It may not detect the disease in its early stages. Additionally, a positive result doesn't necessarily mean the patient is currently infected, as IgG antibodies can remain in the bloodstream long after the infection has cleared.

When is Dengue IgG Antibody - ELISA required?

Dengue IgG Antibody - ELISA (Enzyme-Linked Immunosorbent Assay) is a diagnostic test recommended under certain situations. These include:

  • When a person presents symptoms consistent with dengue fever, such as high fever, severe headache, pain behind the eyes, muscle and joint pains, rash, and mild bleeding (e.g., nose or gums bleed, easy bruising).
  • When a person has recently travelled to or resides in an area known to have cases of dengue fever and presents symptoms consistent with the disease.
  • When a person has been previously diagnosed with dengue fever and is suspected to have a secondary infection.
  • When a person has been exposed to the dengue virus and is being tested for immunity level against the virus.

Who requires Dengue IgG Antibody - ELISA?

There are several groups of people who may require the Dengue IgG Antibody - ELISA test. These include:

  • Individuals who are showing symptoms of dengue fever, especially if they live in or have recently travelled to an area where the disease is common.
  • People who have had dengue fever in the past and are suspected to have a secondary infection. This is because the body produces IgG antibodies in response to the infection, and these can help determine whether a person has been infected again.
  • Healthcare providers may also use this test to monitor a person’s immune response to the dengue virus over time, particularly in areas where the disease is common.
  • People who have been exposed to the dengue virus and are being tested for immunity level against the virus.

What is measured in Dengue IgG Antibody - ELISA?

The Dengue IgG Antibody - ELISA test measures the following:

  • The presence and concentration of IgG antibodies against the dengue virus in the blood. These antibodies are produced by the immune system in response to a dengue infection.
  • The test can help determine whether a person has been infected with the dengue virus in the past and has developed immunity to it.
  • The test can also help differentiate between primary and secondary dengue infections. In a primary infection, IgG antibodies are produced at a slower rate and at lower levels than in a secondary infection.
  • The test can provide valuable information for epidemiological studies, helping to track the prevalence and spread of the dengue virus in a population.

What is methodology of Dengue IgG Antibody - ELISA?

  • The Dengue IgG Antibody - ELISA test is a method used to detect and measure antibodies produced by the body in response to a Dengue virus infection.
  • ELISA stands for Enzyme-Linked Immunosorbent Assay. It is a laboratory technique used to detect the presence of specific antibodies or antigens in a sample.
  • In the context of Dengue, it is used to detect the Dengue IgG antibodies. These are produced by the immune system several days after infection, and their presence suggests a past infection with the Dengue virus.
  • The test involves adding a patient's blood sample to a plate coated with Dengue antigen. If Dengue IgG antibodies are present in the sample, they will bind to the antigen.
  • Next, an enzyme-linked antibody that can bind to human IgG antibodies is added. If the patient's sample contained Dengue IgG antibodies, they will now be linked to the enzyme.
  • A substrate is then added, which the enzyme can convert into a detectable signal. The intensity of this signal corresponds to the amount of Dengue IgG antibodies in the patient's sample.

How to prepare for Dengue IgG Antibody - ELISA?

  • No specific preparation is needed for the Dengue IgG Antibody - ELISA test.
  • You may be asked to wear a shirt with short sleeves or a sleeve that can be easily rolled up.
  • The test involves a simple blood draw, so if you have a fear of needles or faint at the sight of blood, you should inform your healthcare provider beforehand.
  • It's advisable to eat and drink normally before the test, unless instructed otherwise by your healthcare provider.

What happens during Dengue IgG Antibody - ELISA?

  • During the Dengue IgG Antibody - ELISA test, a healthcare provider will draw a blood sample from a vein in your arm using a small needle.
  • The needle may cause a brief pinching or stinging sensation.
  • The blood sample will then be sent to a laboratory where the ELISA test will be carried out to detect the presence and quantity of Dengue IgG antibodies.
  • The results will be interpreted by a healthcare provider who will then discuss them with you.
  • Depending on the results, further tests may be needed to confirm the diagnosis and determine the best treatment approach.

What is Dengue IgG Antibody - ELISA normal range?

The Dengue IgG Antibody - Enzyme-Linked Immunosorbent Assay (ELISA) is a diagnostic test used to detect antibodies produced by the immune system in response to a dengue infection. The normal range of Dengue IgG Antibody in the blood is typically less than 20 AU/ml. Any result above this threshold may indicate a recent or past infection.


What are reasons for abnormal Dengue IgG Antibody - ELISA normal range?

  • A high level of Dengue IgG antibodies could mean that you have been infected with the dengue virus. This high level could be due to a recent infection or a past infection.

  • False-positives can also occur, leading to an abnormal Dengue IgG Antibody - ELISA result. This can happen due to cross-reactivity with other flaviviruses such as Zika or Yellow Fever viruses.

  • Having undergone a vaccination for dengue can also lead to an increased level of Dengue IgG antibodies.


How to maintain normal Dengue IgG Antibody - ELISA range?

  • Maintain a healthy lifestyle to boost your immune system. This includes having a balanced diet, regular exercise, and enough sleep.

  • Avoid mosquito bites, especially in areas known for dengue infections. Use mosquito repellents, wear long-sleeved clothes and use mosquito nets.

  • Get vaccinated for dengue if it's available in your country. The vaccine can help your body build immunity against the dengue virus.

  • Regular check-ups with your healthcare provider can also help monitor your antibody levels and detect any abnormality early.


Precautions and Aftercare tips post Dengue IgG Antibody - ELISA?

  • After the test, it's important to discuss the results with your healthcare provider. They can help you understand what the results mean and what steps to take next.

  • If the results indicate a recent or past infection, follow your healthcare provider's advice on treatment and care. This may include taking prescribed medication, getting plenty of rest, and drinking lots of fluids.

  • Even after recovery from a dengue infection, continue to take precautions to avoid mosquito bites. This is because a second infection with a different strain of the dengue virus can lead to severe dengue.

  • Regular follow-ups with your healthcare provider are also crucial. They can monitor your recovery and ensure that your Dengue IgG antibody levels return to the normal range.


Why Book with Bajaj Finserv Health?

There are numerous reasons why choosing Bajaj Finserv Health for your medical needs is the right choice. Here are a few key reasons:

  • Precision: All labs recognized by Bajaj Finserv Health are equipped with the latest technologies to deliver highly accurate results.
  • Cost-Effective: Our individual Diagnostic tests and services are very thorough yet affordable, ensuring you don't have to worry about financial strain.
  • Home Sample Collection: We provide the convenience of collecting your samples from your home at a time that suits you best.
  • Nationwide Coverage: Our medical test services are accessible regardless of your location in the country.
  • Convenient Payments: We offer multiple payment options, including cash and digital payments, for your convenience.

Note:

This is not medical advice, and this content should only be considered for informational purposes only. Consult with your healthcare provider for individual medical guidance.

Frequently Asked Questions

How to maintain normal Dengue IgG Antibody - ELISA levels?

Avoiding dengue infection is the key to maintaining normal Dengue IgG Antibody - ELISA levels. This can be achieved by preventing mosquito bites, which are the primary transmitters of the dengue virus. It is essential to use mosquito repellents, wear long sleeves and pants, and keep windows and doors screened. Additionally, maintaining a clean surrounding environment can prevent the breeding of mosquitoes.

What factors can influence Dengue IgG Antibody - ELISA Results?

The Dengue IgG Antibody - ELISA results can be influenced by several factors. These include the timing of the test, as the presence of antibodies usually increases a week after the onset of symptoms. Another significant factor is the patient's immune response. People with a stronger immune response may produce more antibodies, affecting the results. Any recent infections can also impact the results.

How often should I get Dengue IgG Antibody - ELISA done?

The Dengue IgG Antibody - ELISA test is typically done when there is a suspicion of dengue fever. In endemic areas, it may be done as a routine test during fever outbreaks. However, there are no specific guidelines on the frequency of this test. It should be done based on the doctor's advice depending on the individual's health condition and exposure risk.

What other diagnostic tests are available?

Besides the Dengue IgG Antibody - ELISA test, other diagnostic tests for dengue include the NS1 antigen test, which can detect the virus soon after infection, and the Dengue IgM antibody test, which can detect a recent dengue infection. Additionally, PCR tests can also identify the presence of the dengue virus in the blood.

What are Dengue IgG Antibody - ELISA prices?

The cost of the Dengue IgG Antibody - ELISA test can vary based on the location and the specific laboratory. Generally, the price can range from $20 to $100. However, it's recommended to check with the local clinics or laboratories for the exact pricing details.