Last Updated 1 November 2024

What is Glucose Tolerance Test (GTT-2)

The Glucose Tolerance Test (GTT-2) is a diagnostic procedure used to check how your body metabolizes sugar. It is typically used to diagnose conditions like diabetes and insulin resistance.

  • Purpose: GTT-2 is primarily used to diagnose diabetes in pregnancy (gestational diabetes). It may also detect type 2 diabetes or prediabetes in non-pregnant individuals.
  • Procedure: The test involves fasting overnight, after which a baseline blood sample is taken. Then, the patient drinks a liquid containing a high concentration of glucose. Blood samples are taken again at 1 hour and 2 hours after the drink to measure how the body processes glucose.
  • Interpretation: If your blood sugar level is higher than normal 2 hours after drinking the glucose solution, you may have diabetes or prediabetes.
  • Risks: The risks of the GTT-2 are minimal but may include feeling lightheaded, sweating, or fainting due to hypoglycemia (low blood sugar).
  • Lifestyle changes: If the test results indicate diabetes or prediabetes, lifestyle changes such as regular exercise, a healthy diet, and maintaining a healthy weight can help manage blood glucose levels.
  • Medical treatment: Depending on the results of the test, medication may be prescribed to help control blood sugar levels.

In conclusion, the Glucose Tolerance Test (GTT-2) is a valuable tool in diagnosing and managing conditions related to blood sugar. By understanding how your body processes glucose, you and your healthcare provider can work together to develop an effective treatment plan.


When is Glucose Tolerance Test (GTT-2) required?

The Glucose Tolerance Test (GTT-2) is often required in circumstances where an individual is suspected to have a certain type of diabetes or is at risk of developing diabetes. The test is primarily used to diagnose and monitor the condition. Here are some specific scenarios when a GTT-2 may be required:

  • Pregnancy: During pregnancy, women are often screened for gestational diabetes, a temporary form of diabetes that can occur during pregnancy. The GTT-2 test is used to diagnose this condition.
  • Pre-diabetes: This test is required if you have pre-diabetes. This is a condition where your blood sugar levels are higher than normal, but not yet high enough to be diagnosed as diabetes.
  • Unexplained symptoms: If you are experiencing unexplained symptoms such as excessive thirst, frequent urination, and unexplained weight loss, a GTT-2 may be required to rule out diabetes.

Who requires Glucose Tolerance Test (GTT-2)?

There are several groups of people who may require a GTT-2. These include:

  • High-risk individuals: People who have a family history of diabetes, are overweight, or have other risk factors are often recommended to get a GTT-2.
  • Pregnant women: As mentioned earlier, pregnant women are often screened for gestational diabetes using a GTT-2.
  • People with pre-diabetes: Those who have been diagnosed with pre-diabetes may require regular GTT-2 tests to monitor their condition.
  • Individuals with unexplained symptoms: If you're experiencing symptoms that could indicate diabetes, your doctor may recommend a GTT-2.

What is measured in Glucose Tolerance Test (GTT-2)?

The following are measured in a Glucose Tolerance Test (GTT-2):

  • Blood Glucose Level: The main purpose of the GTT-2 is to measure the level of glucose in your blood. This is done by taking a fasting blood sample, then giving you a sugary drink and taking further blood samples at regular intervals. The way your body processes the sugar can indicate whether you have diabetes.
  • Insulin Response: The test may also measure your body's insulin response. If your body is not producing enough insulin, or if the insulin is not working properly, this can cause your blood glucose level to rise.

What is the Methodology of Glucose Tolerance Test (GTT-2)?

  • The Glucose Tolerance Test (GTT-2) is a medical procedure that measures the body's ability to metabolize glucose. It is primarily used to diagnose diabetes, gestational diabetes, and insulin resistance.
  • The test begins with the patient fasting for 8 to 12 hours. After this period, the patient's baseline blood sugar level is measured.
  • A high-dose glucose solution is then given to the patient to drink. The solution typically contains 75 grams of glucose. This triggers the body to produce insulin to help absorb the glucose.
  • Subsequent blood samples are then taken every 30 to 60 minutes after the glucose drink has been consumed. This is done for a period of two hours. These samples are used to measure how well the patient's body processes the glucose over time.
  • If the body is unable to metabolize the glucose effectively, the blood sugar levels will remain high. This could indicate a diagnosis of diabetes or insulin resistance.

How to Prepare for the Glucose Tolerance Test (GTT-2)?

  • It is important for patients to fast for 8 to 12 hours prior to the test. Only water is allowed during this fasting period.
  • Patients are advised to avoid strenuous physical activity and refrain from smoking for at least 3 days before the test, as these could affect the results.
  • Inform your doctor about any medications you are currently taking, as certain medications could interfere with the test results.
  • Patients are also advised to maintain their usual diet and physical activity level in the days leading up to the test.

What Happens During the Glucose Tolerance Test (GTT-2)?

  • Upon arrival at the testing facility, a blood sample is taken from the patient to measure the fasting blood sugar level.
  • The patient is then given a glucose solution to drink. The solution is sweet and should be consumed within 5 minutes.
  • After drinking the solution, the patient will wait for two hours without eating or drinking anything else. During this time, blood samples are taken at regular intervals to measure the blood glucose levels.
  • The procedure is painless, although some patients may experience mild discomfort from the needle used to draw blood. Others may feel a bit light-headed or nauseous from the high sugar content in the glucose solution.
  • The test results are usually available within a few days. Your doctor will discuss the results with you and explain what they mean for your health.

What is Glucose Tolerance Test (GTT-2) normal range?

The Glucose Tolerance Test (GTT-2) is a medical procedure used to monitor an individual's body response in processing glucose, which is a type of sugar. The test is often used to diagnose diabetes, which is a condition characterized by high blood sugar levels. The normal range for a GTT-2 test is usually between 70 to 140 mg/dL. However, glucose levels may vary depending on factors like age, overall health, and whether the test was conducted in a fasted or non-fasted state.


What are reasons for abnormal Glucose Tolerance Test (GTT-2) normal range?

An abnormal Glucose Tolerance Test (GTT-2) normal range could be due to many factors. Some of these include:

  • Diabetes: This is the most common reason for abnormal GTT-2 results. With type 1 diabetes, the body does not produce insulin. With type 2 diabetes, the more common type, the body does not use insulin properly.
  • Prediabetes: This is a condition where the blood sugar is high, but not high enough to be diagnosed as diabetes.
  • Gestational diabetes: This form of diabetes happens during pregnancy and can result in high GTT-2 results.
  • Insulin resistance: This is a condition where the body's cells do not respond properly to insulin, leading to high blood sugar levels.
  • Other medical conditions: Certain conditions like Cushing's syndrome, polycystic ovary syndrome, and hyperthyroidism can also cause abnormal GTT-2 results.

How to maintain normal Glucose Tolerance Test (GTT-2)range?

Maintaining a normal GTT-2 range can be achieved through:

  • Maintaining a healthy diet: Consuming a balanced diet that is rich in whole grains, fruits, and vegetables can help maintain normal glucose levels.
  • Regular exercise: Engaging in physical activity on a regular basis can help the body use glucose more efficiently.
  • Regular monitoring: Regularly monitoring your blood sugar levels can help identify any potential issues early.
  • Weight management: Maintaining a healthy weight can help prevent type 2 diabetes and other conditions that can lead to abnormal GTT-2 results.
  • Medication: If you have been diagnosed with a condition that affects your body's ability to process glucose, medication may be necessary to maintain normal GTT-2 results.

Precautions and Aftercare tips post Glucose Tolerance Test (GTT-2)?

After undergoing a GTT-2 test, the following precautions and aftercare tips can be helpful:

  • Post-test monitoring: Monitor your blood sugar levels after the test to ensure they return to normal.
  • Hydration: Drink plenty of water after the test to help flush out any excess glucose from your system.
  • Rest: Allow your body to rest and recover after the test, especially if you experienced any side effects like dizziness or fatigue.
  • Follow-up appointments: Schedule and attend all follow-up appointments with your healthcare provider to discuss your results and any necessary next steps.
  • Medication: If you have been prescribed medication to manage your blood sugar levels, ensure to take it as directed by your healthcare provider.

Why Book with Bajaj Finserv Health?

  • Precision: Every laboratory recognized by Bajaj Finserv Health is equipped with advanced technologies to provide you with the most precise results.
  • Cost-effectiveness: The individual diagnostic tests and services we offer are all-encompassing and won't put a significant dent in your budget.
  • Home-based sample collection: For your convenience, you can opt to have your samples collected from your home at a time that suits you best.
  • Nationwide availability: Our medical test services can be availed regardless of your location in the country.
  • Flexible payment methods: You have the option to choose from a variety of payment methods, including both cash and digital options.

Note:

This is not medical advice, and this content should only be considered for informational purposes only. Consult with your healthcare provider for individual medical guidance.