IgE Total antibody

Also Know as: Allergy blood test, Sr. IgE

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Last Updated 1 November 2024

What is IgE Total antibody

  • IgE Total antibody, or Immunoglobulin E, is a type of antibody that is primarily found in the lungs, skin, and mucous membranes.
  • It plays an essential role in the body's immune system particularly in the allergic response.
  • When an individual has an allergy, the immune system produces IgE antibodies against the allergen. These antibodies bind to immune cells in the skin, lungs, and mucous membranes and cause these cells to release various chemicals when exposed to the allergen.
  • One of these chemicals is histamine, which triggers the symptoms of an allergic reaction, such as itching, redness, swelling, and mucus production.
  • The amount of IgE antibodies in the blood can be a marker of how the body's immune system is responding to an allergy-causing substance.
  • A blood test can be done to measure the amount of IgE in the body to diagnose allergies, asthma, and other conditions that can cause an increase in IgE levels.
  • High levels of IgE may also indicate a parasitic infection or a rare immune system disorder known as hyper IgE syndrome.
  • It's important to note that even if IgE levels are normal, it's still possible to have a significant allergic reaction.
  • Research is currently ongoing to develop treatments that can block IgE antibodies and potentially prevent or reduce the severity of allergic reactions.

When is IgE Total Antibody Required?

Immunoglobulin E (IgE) total antibody test is often required under several circumstances. These may include:

  • Allergic Disease Diagnosis: The IgE total antibody test is crucial for diagnosing allergic diseases. Allergies occur when the immune system overreacts to substances like pollen, pet dander, certain foods, insect stings, or medications. IgE antibodies play a significant role in these reactions, making the test a valuable tool for determining the presence of allergies.
  • Asthma: Asthma is a chronic condition that causes inflammation and narrowing of the bronchial tubes. Elevated IgE levels can indicate a high risk of asthma or signal that the condition is worsening.
  • Parasitic Infections: Parasites often trigger an IgE response. Therefore, the IgE total antibody test might be required to confirm or rule out a parasitic infection.

Who Requires IgE Total Antibody?

Several groups of individuals may require an IgE total antibody test. These include:

  • Allergy Sufferers: Individuals who have symptoms of allergies such as sneezing, itching, rash, wheezing, or anaphylaxis may require an IgE total antibody test to identify the cause of their symptoms.
  • Asthma Patients: Asthma patients can benefit from IgE total antibody tests as they can provide information on the severity of the condition and guide the treatment plan.
  • Individuals with Suspected Parasitic Infections: If a person is suspected of having a parasitic infection, especially if they have traveled to an area where such infections are common, an IgE total antibody test may be necessary.

What is Measured in IgE Total Antibody?

The IgE total antibody test measures several elements, including:

  • Total IgE Levels: This is the overall amount of IgE in the blood. High levels can indicate an allergic reaction or a parasitic infection.
  • Specific IgE Levels: This test measures the amount of IgE that reacts to specific allergens. This can help identify the substances causing allergic reactions.
  • Elevated IgE Levels: This can indicate a severe allergic response or a parasitic infection. It may also suggest other medical conditions like certain immune disorders or cancers.

What is the Methodology of IgE Total Antibody?

  • The Immunoglobulin E (IgE) total antibody test is a blood test used to measure the levels of IgE, a type of antibody.
  • Antibodies are produced by the immune system to fight against antigens, such as bacteria, viruses, and allergens.
  • IgE antibodies are found in the lungs, skin, and mucous membranes. They are primarily associated with allergic reactions; when you have an allergy, your immune system overreacts and produces unnecessary IgE antibodies.
  • The methodology of the IgE Total Antibody test involves a simple blood draw. The blood sample is then analyzed in a laboratory for the presence and amount of IgE antibodies.
  • The test results can help doctors diagnose and monitor allergies and certain immune system disorders.

How to Prepare for IgE Total Antibody Test?

  • No special preparation is needed for this test. However, it is crucial to inform your doctor about any medications, vitamins, or supplements you are taking, as some can interfere with the test results.
  • Some doctors may ask you to stop taking certain medications before the test.
  • Always follow your doctor's instructions regarding preparation for the test to ensure its accuracy.

What Happens During IgE Total Antibody Test?

  • The IgE total antibody test is a standard blood test.
  • A healthcare provider will clean an area of your skin, usually the inside of your elbow or the back of your hand, using an antiseptic wipe.
  • They will then insert a small needle into a vein to collect a blood sample. You may feel a quick sting or prick when the needle goes in.
  • Once enough blood has been collected, the provider will remove the needle and cover the insertion site with a bandage or cotton ball to stop any bleeding.
  • The blood sample is then sent to a laboratory for analysis.
  • The procedure usually takes less than five minutes, and you can go home immediately afterward.

What is IgE Total antibody normal range?

The Immunoglobulin E (IgE) is a type of antibody that is only found in mammals. These antibodies are made by the immune system to fight certain infections, mainly those caused by parasites. They also play a significant role in allergic reactions.

  • The normal range for IgE differs by age and is typically measured in International Units per Millilitre (IU/mL).
  • For infants, the normal range is usually less than 15 IU/mL.
  • For children, the normal range is usually less than 60 IU/mL.
  • For adults, the normal range is usually less than 100 IU/mL.

What are reasons for abnormal IgE Total antibody normal range?

Having an abnormal IgE Total antibody normal range can be due to a variety of reasons:

  • Allergies: Increased levels of IgE antibodies are often seen in cases of allergic reactions. This includes food allergies, allergic asthma, and atopic dermatitis.
  • Infections: Certain parasitic infections can cause an increase in IgE levels.
  • Autoimmune diseases: Conditions such as systemic lupus erythematosus and rheumatoid arthritis can also result in elevated IgE levels.
  • Immunodeficiency disorders: Conditions that affect the immune system, such as Hyper IgE Syndrome, can cause abnormally high levels of IgE.
  • Certain types of cancer: Some forms of cancer, particularly those affecting the immune system like multiple myeloma or lymphoma, can result in an increased IgE level.

How to maintain normal IgE Total antibody range?

Maintaining a normal IgE Total antibody range involves managing and preventing conditions that can cause abnormal levels. Here are some tips:

  • Avoid allergens: If you have allergies, avoid exposure to allergens as much as possible. This includes food allergens, dust, pollen, and pet dander.
  • Stay healthy: Maintain a healthy lifestyle. Regular exercise, a balanced diet, and sufficient sleep can help boost your immune system.
  • Manage stress: High levels of stress can negatively impact your immune system. It’s important to find healthy ways to manage stress like yoga, meditation, or other relaxation techniques.
  • Regular check-ups: Regular medical check-ups can help detect any underlying conditions that might affect your IgE levels.

Precautions and Aftercare tips post IgE Total antibody?

After getting an IgE Total antibody test, there are some precautions and aftercare tips to follow:

  • Follow your doctor's advice: If your IgE levels are abnormal, it’s crucial to follow your doctor's advice. This might include medication, lifestyle changes, or additional testing.
  • Monitor symptoms: If you have allergies or other conditions that can affect your IgE levels, monitor your symptoms closely. Seek medical help if your symptoms worsen.
  • Proper aftercare: If your test involved a blood draw, make sure to take care of the puncture site to prevent infection.
  • Stay hydrated: Keeping hydrated before and after a blood test can help with blood flow and recovery.

Why Book with Bajaj Finserv Health?

  • Precision: Bajaj Finserv Health approved laboratories employ state-of-the-art technologies, ensuring the utmost accuracy of your results.
  • Cost-effectiveness: Our standalone Diagnostic tests and providers are extensive and won't put a strain on your budget.
  • Home sample collection: We provide the convenience of having your samples picked up from your home at a time that suits you best.
  • Nationwide coverage: Regardless of your location in the country, our medical test services are accessible to you.
  • Flexible payments: Choose from a variety of payment methods, including cash or digital options.

Note:

This is not medical advice, and this content should only be considered for informational purposes only. Consult with your healthcare provider for individual medical guidance.

Frequently Asked Questions

What infections/illnesses does IGE total Test detect?

It detects the presence of an allergic response to one or multiple allergens. It cannot specify a particular allergen.

What happens if IGE level is high?

Although high IGE levels themselves are not life-threatening, the allergen themselves can mount a severe reaction. Log-term increased levels if IGE total are associated with low risk of developing some types of cancers.

Is fasting required for IGE total test?

No. You can continue to eat and drink like you usually do.

What is Total IGE Normal Range?

1 month old baby: <1.5 IU/ml 1month to 1 year: <15 IU/ml 1-5 years of age: <60 IU/ml 5-9 years of age: <90 IU/ml 9-15 years of age: <200 IU/ml >15 years of age: <100 IU/ml.

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