What is CA-15.3, Serum

What is CA-15.3, Serum

CA-15.3 stands for Cancer Antigen 15.3, a protein that is a biomarker often used in the monitoring and management of certain types of cancer, particularly breast cancer. The CA-15.3, Serum test is a blood test that measures the level of CA-15.3 in the serum, the liquid part of the blood.

• CA-15.3 is produced by normal breast cells, but in women with breast cancer, levels of CA-15.3 may be elevated. The test is used alongside other tests and procedures to monitor the disease.

• The CA-15.3 test is not used for cancer screening or diagnosis because many non-cancerous conditions can also increase the CA-15.3 level. Moreover, not all women with breast cancer have elevated CA-15.3.

• The primary use of the CA-15.3 test is to monitor response to breast cancer treatment and to check for cancer recurrence in women who have been previously treated for breast cancer.

• If the CA-15.3 level decreases during treatment, it usually indicates that the cancer is responding to treatment. If the CA-15.3 level increases, it may suggest that the cancer is not responding to treatment or is recurring.

• It is important to remember that a single elevated CA-15.3 test result does not necessarily indicate a poor prognosis. The trend of CA-15.3 levels over time is often more meaningful than a single result.

When is CA-15.3, Serum required?

CA-15.3, Serum is required in several instances. The CA-15.3 is a protein that is produced by normal breast cells. In many people with cancerous breast tumors, levels of CA-15.3 are elevated. This protein is thus not used to screen for breast cancer, but to monitor the treatment in women diagnosed with breast cancer, particularly advanced breast cancer. The key instances where this serum is required include:

• Following the therapy for breast cancer: After the initial therapy, CA-15.3 levels are often measured to ensure that the treatment was effective and the cancer has not recurred. An increase in the CA-15.3 level may indicate a recurrence of the disease.
• During ongoing treatment for breast cancer: For women undergoing treatment for advanced breast cancer, CA-15.3 levels are often measured regularly to monitor the effectiveness of the treatment. A decrease in CA-15.3 level may indicate the treatment is working, while an increase may suggest the need for a change in treatment.

Who requires CA-15.3, Serum?

The CA-15.3, Serum is required primarily by women who have been diagnosed with breast cancer. The following groups of people specifically require this test:

• Women diagnosed with breast cancer: If a woman is diagnosed with breast cancer, particularly advanced breast cancer, CA-15.3 levels are often measured regularly to monitor the effectiveness of the treatment.
• Women undergoing therapy for breast cancer: After the initial therapy for breast cancer, CA-15.3 levels are often measured to monitor for recurrence of the disease. An increase in the CA-15.3 level may indicate a recurrence of the disease.

What is measured in CA-15.3, Serum?

In the CA-15.3, Serum test, the level of CA-15.3 protein in the blood is measured. The following aspects are covered:

• CA-15.3 Levels: This test measures the amount of protein called CA-15.3 in the blood. It is produced by normal breast cells, but in many people with cancerous breast tumors, levels of this protein are elevated.
• Effectiveness of Treatment: The test is often used to monitor the effectiveness of breast cancer treatment. If levels decrease, it may indicate that the treatment is working, while an increase could suggest that the disease is not responding to treatment and a different approach may be needed.
• Recurrence of Disease: After the initial therapy, this test can help monitor for recurrence of the disease. An increase in the CA-15.3 level may indicate a recurrence of the disease.

What is methodology of CA-15.3, Serum?

• CA-15.3, also known as Cancer Antigen 15.3, is a protein that is typically overexpressed in certain types of cancers, especially breast cancer.
• The methodology of the CA-15.3, Serum test, involves the detection of this protein in the blood. High levels of CA-15.3 can indicate the presence of cancer or other abnormal conditions.
• CA-15.3 testing is generally used for monitoring purposes after a breast cancer diagnosis. It helps to track the effectiveness of treatment and to detect a recurrence of the disease.
• However, it's important to note that CA-15.3 is not a diagnostic test for cancer. Its levels can be elevated in other conditions, including liver disease, tuberculosis, and benign breast or ovarian disease.
• The test is usually performed on a blood sample, which is sent to a lab for analysis. The process involves the use of an immunoassay, a biochemical test that measures the concentration of the CA-15.3 protein.

How to prepare for CA-15.3, Serum?

• No special preparation is usually needed for a CA-15.3, Serum test. However, it's crucial to inform your doctor about any medications or supplements you're taking, as they may affect the test results.
• Since the test involves drawing blood, you might want to wear a short-sleeved shirt or a shirt with sleeves that can be rolled up.
• Before the test, you will typically be asked to sign a consent form. Make sure to read it carefully and ask any questions you might have.
• Remember to stay calm and relaxed. The test is generally quick and causes minimal discomfort.

What happens during CA-15.3, Serum?

• During a CA-15.3, Serum test, a healthcare provider will draw a sample of your blood. This is usually done from a vein in your arm.
• First, the area around the vein will be cleaned with an antiseptic. Then, a tourniquet (an elastic band) will be placed around your upper arm to apply pressure and cause the veins to swell with blood.
• Next, a needle will be inserted into a vein, and blood will be drawn into a vial or syringe. The needle will then be removed, and a small bandage will be applied to the puncture site.
• The blood sample will then be sent to a lab for analysis. The results of your test will be sent to your doctor, who will discuss them with you.
• During the test, you might feel a slight sting or prick when the needle is inserted, but the discomfort is usually minimal and brief.

What is CA-15.3?

CA-15.3, also known as Carbohydrate Antigen 15.3, is a type of protein produced by normal breast cells. However, in certain conditions like breast cancer, the levels of this protein may increase in the body. The CA-15.3 test is used as a tumor marker to monitor treatment in women diagnosed with breast cancer.

Serum Normal Range

The normal range for CA-15.3 in the blood serum is usually less than 30 units per milliliter (U/mL). However, normal range values may vary slightly among different laboratories. It’s necessary to consult with healthcare providers to understand the specific test results.

Reasons for Abnormal CA-15.3 Serum Normal Range

• Breast Cancer: CA-15.3 levels are often elevated in women with breast cancer, especially in advanced stages.
• Other Cancers: Increased CA-15.3 levels can also be found in individuals with ovarian, lung, and prostate cancer.
• Non-cancerous Conditions: Certain conditions like liver disease, sarcoidosis, and tuberculosis may cause elevated CA-15.3 levels.
• Physiological Conditions: Pregnancy and lactation can sometimes lead to increased CA-15.3 levels.

How to Maintain Normal CA-15.3 Serum Range

• Regular Screening: Routine medical checkups and screenings help detect any abnormal increase in CA-15.3 levels early on.
• Healthy Lifestyle: Maintain a healthy lifestyle with balanced diet and regular exercise.
• Limited Alcohol: Limit alcohol intake as it may increase the risk of breast cancer, thereby increasing CA-15.3 levels.
• No Smoking: Avoid smoking as it is a known risk factor for many types of cancer.

Precautions and Aftercare Tips Post CA-15.3 Serum

• Follow-Up Tests: If the CA-15.3 levels are high, healthcare providers may suggest more diagnostic tests to identify the underlying cause.
• Regular Monitoring: Regular monitoring of CA-15.3 levels is necessary for individuals undergoing treatment for breast cancer.
• Healthy Habits: Maintain healthy habits post the test to help control and maintain normal levels of CA-15.3.
• Mental Support: Seek mental and emotional support, if needed, especially for individuals undergoing cancer treatment.
• Communication: Keep an open line of communication with healthcare providers. Discuss all concerns related to CA-15.3 levels, its implications, and necessary precautions.

Why Book with Bajaj Finserv Health?

With Bajaj Finserv Health, you get the assurance of:

• Precision: All of our affiliated labs employ cutting-edge technologies ensuring you get the most precise results.
• Cost-Effectiveness: Our individual Diagnostic tests and services are quite extensive yet won't put a dent in your wallet.
• Home Sample Collection: We offer the convenience of collecting your samples from your home at a time that suits you best.
• Nationwide Availability: Regardless of your location within the country, our medical test facilities are accessible.
• Convenient Payment Options: Choose from our diverse payment options, be it cash or digital.