Absolute Neutrophil Count, Blood

Also Know as: ANC, ABS NEUTROPHIL

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Last Updated 1 November 2024

What is ANC Test?

The Absolute Neutrophil Count (ANC) measures the number of neutrophil granulocytes in the blood. Neutrophils are white blood cells that fight infection. The absolute neutrophil count (ANC) determines the quantity of neutrophil granulocytes, or neutrophils, in the blood. Neutrophil cells are white blood cells used in the fight against infection. The total number of white blood cells are used to compute ANC; these values are typically based on the percentage of mature neutrophils and bands, which are immature neutrophils. Low ANC (neutropenia) may result from diseases that damage the bone marrow, infections, or treatments like chemotherapy.

  • Elevated ANC (neutrophilia) may be seen in various conditions, including bacterial infections, inflammation, stress, and leukemia.

  • The ANC is not measured directly. It's derived from the total white blood cell (WBC) count and the percentage of neutrophils observed in a manual count of 100 white blood cells (neutrophil %).

  • The formula to calculate ANC is ANC = Total WBC count * Neutrophil %.

  • The normal range for ANC is 1.5 to 8.0 (1,500 to 8,000/mm3).

  • When ANC falls below 1,000/mm3, the risk of infection increases. The lower the ANC count, the greater the risk.

  • Doctors may use the ANC to monitor a person's immune system, particularly in people undergoing chemotherapy or those with conditions that affect the bone marrow.


When is ANC Test Required?

The Absolute Neutrophil Count (ANC) in the blood test is required in various situations. It is an important marker to understand the state of a person's immune system. Here are some scenarios when an ANC Blood test might be required:

  • When a person is undergoing chemotherapy, the treatment can drastically affect the neutrophil count in the blood.

  • For patients suffering from conditions that affect the bone marrow, such as leukemia.

  • For those with severe infections, neutrophils are essential to the body's defense against bacterial infections.

  • Monitor the course and effectiveness of treatment for individuals diagnosed with neutropenia (a condition typified by an unusually low blood neutrophil count).


Who Requires ANC Test?

A specific group typically requires the Absolute Neutrophil Count, Blood test of people. This includes:

  • Individuals using radiation therapy or chemotherapy to treat cancer, as these therapies can significantly affect the production of neutrophils.

  • Individuals are diagnosed with conditions that affect the production of neutrophils, such as aplastic anemia or certain types of leukemia.

  • Persons suffering from severe or recurrent infections might indicate an issue with their immune system's ability to fight off bacteria and require further investigation.

  • People who are on certain types of medications that can potentially affect the production of neutrophils in the bone marrow.


What is Measured in ANC Test?

The Absolute Neutrophil Count Blood test measures the following:

  • The number of neutrophils, a type of white blood cell, present in a specific blood volume. This count is usually given in cells per microliter.

  • The percentage of neutrophils compared to other types of white blood cells is essential, as a high or low percentage can indicate certain medical conditions.

  • The total white blood cell count and the neutrophil percentage are used to compute the Absolute Neutrophil Count (ANC), which gives a clearer picture of the immune system's capacity to fight infections


What is the Methodology of ANC Test?

  • The Absolute Neutrophil Count (ANC) measures the number of neutrophil granulocytes in the blood.

  • Measurements of the total number of white blood cells are used to compute the ANC, which is typically determined by adding together the fraction of mature neutrophils (also called polymorphonuclear leukocytes, PMNs, or segmented cells) and bands, which are immature neutrophils.

  • The ANC is not measured directly. The WBC count multiplied by the percentage of neutrophils in the differential WBC count yields the result. The segmented (completely developed) neutrophils plus the bands (nearly mature neutrophils) make up the % of neutrophils.

  • The complete blood count (CBC) is a more comprehensive blood panel that details the many types of cells in the blood, including the ANC.

  • This test is often used to monitor treatment during chemotherapy, which can cause neutropenia or a low neutrophil count, leading to an increased risk of infection.


How to Prepare for the ANC Test?

  • No special preparation is needed for the ANC blood test.

  • It is imperative that you let your doctor know about any vitamins, supplements, or medications you are taking, though, as some medications may have an adverse effect on the test findings.

  • The test requires a blood sample drawn from a vein in the arm. When the needle is put, it could sting a little.

  • It's good practice to hydrate well before the test, as this makes the vein more visible and the blood draw easier.


What Happens During the ANC Test?

  • During the ANC test, a medical professional will use an antiseptic wipe to clean a small portion of your skin.

  • Your arm vein will be punctured with a tiny needle that is connected to a test tube. The amount of discomfort you feel will depend on the skill of the health professional, the condition of your veins, and your pain sensitivity.

  • When the needle is inserted into your vein, you may feel a quick sting or pinch. Some people also feel a prickling or burning.

  • Once enough blood is collected, the healthcare provider removes the needle and covers the puncture site with a small bandage or cotton ball. You should apply pressure to the site until any bleeding stops.

  • Your blood sample will then be sent to a lab for analysis.


What is ANC Test Normal Range?

  • The normal range for the Absolute Neutrophil Count is between 1500 and 8000 cells per microliter of blood.

  • A count of less than 1500 cells per microliter is considered low and can increase the risk of infection.

  • A count greater than 8000 cells per microliter is considered high, indicating an infection or other medical condition


What are the Reasons for Abnormal Absolute Neutrophil Count?

  • Infections, particularly bacterial infections, can cause an increase in the number of neutrophils.

  • Stress on the body or mind can sometimes increase the number of neutrophils.

  • Various types of leukemia can cause both an increase and decrease in the number of neutrophils.

  • Aplastic anemia and some types of chemotherapy can lead to a reduction in neutrophil counts.


How to Maintain Normal Absolute Neutrophil Count?

  • Consume a healthy, fruit- and vegetable-rich diet to strengthen your immune system and raise your neutrophil count.

  • Get regular exercise, which can help stimulate the production of neutrophils.

  • Avoid exposure to infections, which can lower your neutrophil count.

  • Get regular medical check-ups, which can detect any abnormalities in your neutrophil count early


Precautions and Aftercare Tips Post Absolute Neutrophil Count

  • If your neutrophil count is low, avoid people who are sick, as your body may not be able to fight infections effectively.

  • Avoid touching your face and wash your hands frequently as part of healthy hygiene.

  • If you are on chemotherapy, follow your doctor's advice closely, as this can affect your neutrophil count.

  • See your doctor often to monitor your situation if your neutrophil count is elevated.

  • Eat a diet rich in vitamin B12 and folate, which are needed to produce neutrophils.


Why Book with Bajaj Finserv Health?

  • Precision: All labs recognized by Bajaj Finserv Healthmake use of the newest technologies to guarantee the maximum degree of accuracy in the outcomes.

  • Cost-effective: Our individual diagnostic tests and service providers are pervasive and do not burden your pocket.

  • Home sample collection: We offer the convenience of collecting your samples from your home at a time that is suitable for you.

  • Nationwide availability: Our medical test facilities are accessible regardless of your location within the country.

  • Convenient payment options: You can select from our available payment methods, whether cash or digital.


Note:

This information is not intended as medical advice; individuals should consult with their healthcare provider for personalized guidance.

Frequently Asked Questions

How to maintain normal Absolute Neutrophil Count, Blood levels?

Sustaining a healthy lifestyle is essential to preserving normal levels of the Absolute Neutrophil Count (ANC). This includes a balanced diet, consistent exercise, and enough sleep. Refraining from smoking and binge drinking is also advantageous. Medication or supplements may occasionally be required to control ANC levels. Always seek individual guidance from your healthcare provider.

What factors can influence Absolute Neutrophil Count Results?

Several factors can influence ANC results, including infections, certain medications, and underlying health conditions such as autoimmune diseases or cancer. ANC levels can also be impacted by stress and lifestyle choices such as poor diet and inactivity. It's crucial to address any worries you may have with your healthcare professional in order to better comprehend your outcomes.

How often should I get Absolute Neutrophil Count Test done?

The frequency of ANC testing depends on your personal health situation. If you have a recognized immune system-related illness, your doctor might advise more frequent testing. For individuals in good health, routine blood work is typically sufficient.

What other diagnostic tests are available?

Many diagnostic tests are available depending on your specific health concerns. These may include other types of blood tests, imaging scans, biopsies, or specialized tests for particular conditions. The tests that are best for your circumstances and health objectives can be discussed with your healthcare professional.

What are Absolute Neutrophil Count, Blood prices?

The cost of an ANC test can vary depending on several factors, including the location of the testing, whether or not insurance coverage is available, and the specific laboratory performing the test. It is advised to get the most up-to-date pricing information by contacting your insurance company and healthcare provider.