Bone Marrow Transplant

Bone Marrow Transplant

Find the best hospitals for Bone Marrow Transplant on the Bajaj Finserv Health platform.

Minimum Cost
15,75,000
Average Cost
28,87,500
Maximum Cost
42,00,000
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Bone Marrow Transplant Surgery

Bone marrow transplant surgery is a medical procedure used to treat various illnesses and conditions that affect the blood or bone marrow. It involves replacing the damaged/diseased bone marrow cells with healthy ones to restore the body’s ability to produce blood cells. Bone marrow is a kind of spongy tissue that is found inside bones, which produces platelets, red blood cells and white blood cells that are essential for the body’s immune system.

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Types of Bone Marrow Transplant Procedure

  • Autologous Bone Marrow Transplant

    An autologous bone marrow transplant is a transplant type where the patient receives their own bone marrow cells. Prior to the transplant, the patient’s bone marrow cells are harvested and stored for later use. This type of transplant is typically used for patients who have cancer or other diseases that affect the bone marrow. The goal of this type of transplant is to replace the damaged or diseased cells with healthy ones, thereby restoring the patient’s immune system.

  • Allogenic Bone Marrow Transplant

    An allogenic bone marrow transplant is a type of transplant where the patient receives bone marrow cells from a donor. The donor is typically a family member or a matching donor from a bone marrow registry. This type of transplant is typically used for patients who have leukemia, lymphoma, or other blood-related disorders. The goal of this type of transplant is to replace the patient’s damaged or diseased bone marrow cells with healthy ones from the donor, thereby restoring the patient’s immune system.

  • Syngeneic Bone Marrow Transplant

    A syngeneic bone marrow transplant is a type of transplant where the patient receives bone marrow cells from an identical twin. This type of transplant is typically used for patients who have leukemia or other blood-related disorders. The goal of this type of transplant is to replace the patient’s damaged or diseased bone marrow cells with healthy ones from the donor, thereby restoring the patient’s immune system. In conclusion, bone marrow transplant surgery is a complex medical procedure that is used to treat various illnesses and conditions that affect the blood or bone marrow. There are varying kinds of bone marrow transplant procedures, each with its own unique benefits and risks. It is important for patients to discuss their options with their respective healthcare provider to identify the best course of treatment for their individual needs.

  • When is Bone Marrow Transplant Operation Required?

  • Bone marrow transplant, or stem cell transplant, is a medical procedure used to treat certain types of cancer and other diseases. It involves replacing the diseased or damaged bone marrow with healthy bone marrow cells. Bone marrow is a type of spongy tissue that is present inside the bones that produces blood cells. Bone marrow transplant is required when the patient's bone marrow is not functioning well due to:

  • Cancers like leukemia, lymphoma, and multiple myeloma

  • Genetic disorders like sickle cell anemia, thalassemia, and severe combined immunodeficiency (SCID)

  • Autoimmune diseases like lupus, rheumatoid arthritis, and multiple sclerosis

  • Chemotherapy or radiation therapy for cancer treatment, which can damage the bone marrow The bone marrow transplant process involves the replacement of the damaged bone marrow with healthy bone marrow cells from a donor. The donor can be a family member, an unrelated person, or even the patient themselves if they have stored their own healthy bone marrow cells before undergoing chemotherapy or radiation therapy. The success of the bone marrow transplant depends on several factors, such as the type of disease, the stage of the disease, the age and health of the patient, and the compatibility of the donor's bone marrow cells.

  • How to Prepare for Bone Marrow Transplant Surgery?

    Preparing for bone marrow transplant surgery involves several steps, such as:
  • Medical evaluation:

    The patient will undergo a detailed medical test to determine if they are a suitable candidate for bone marrow transplant surgery. This may involve blood tests, imaging tests, and other diagnostic tests.

  • Donor selection:

    If the patient receives bone marrow cells from a donor, the donor will be chosen as per their compatibility with the patient's bone marrow cells. The donor will also undergo a medical evaluation to ensure they are healthy and suitable for bone marrow donation.

  • Chemotherapy or radiation therapy:

    The patient may need to undergo chemotherapy or radiation therapy to prepare their body for the bone marrow transplant. This is done to kill any leftover cancer cells and suppress the patient's immune system so that it does not attack the donor's bone marrow cells.

  • Bone marrow collection:

    If the patient receives bone marrow cells from a donor, the donor will undergo a bone marrow collection procedure. This involves the insertion of a needle into the donor's hip bone to collect the bone marrow cells. The procedure is done under anesthesia and is generally safe and painless.

  • Transplant procedure:

    The bone marrow transplant procedure itself is done in a hospital setting under general anesthesia. The donor's bone marrow cells are infused into the patient's bloodstream through an IV line. The cells then travel to the patient's bone marrow, where they start producing healthy blood cells.

  • Conclusion:

    bone marrow transplant surgery is a complex medical procedure used to treat certain types of cancer and other diseases. It involves replacing the diseased or damaged bone marrow with healthy cells from a donor. The success of the bone marrow transplant depends on several factors, such as the type of disease, the stage of the disease, the age and health of the patient, and the compatibility of the donor's bone marrow cells. Patients who are scheduled to undergo a bone marrow transplant surgery should undergo a thorough medical evaluation, select a suitable donor, undergo chemotherapy or radiation therapy, and undergo the bone marrow transplant procedure itself in a hospital setting.

    What Happens Before Bone Marrow Transplant Surgery?

  • Medical evaluation:

    Before the bone marrow transplant surgery, the patient will be made to undergo a detailed medical evaluation. This will include blood tests, imaging tests, and other diagnostic tests to determine the overall health of the patient.

  • Matching of donor and recipient:

    For the bone marrow transplant surgery to be successful, the donor's bone marrow must match the recipient's bone marrow. This matching process is done through a series of tests.

  • Preparation for the transplant:

    Once a suitable donor is found, the patient will undergo chemotherapy/radiation therapy to destroy the existing bone marrow. This is done to make room for the new healthy bone marrow cells.

  • Collection of bone marrow cells:

    The donor's bone marrow cells will be collected through a process called bone marrow aspiration. In this process, a needle is inserted into the donor's hip bone and withdrawing a small amount of bone marrow from inside the bone.

  • Cryopreservation:

    The collected bone marrow cells will be frozen and stored until the time that they are ready to be transplanted into the recipient's body.

  • What Happens During Bone Marrow Transplant Operation?

  • Preparation for the transplant:

    Before the bone marrow transplant surgery, the patient will undergo conditioning therapy. This involves high doses of chemotherapy or radiation therapy to kill the existing bone marrow cells and create space for the new healthy bone marrow cells to grow.

  • Transplantation of bone marrow cells:

    The collected bone marrow cells will be thawed and infused into the recipient's bloodstream through a catheter inserted into a vein. The bone marrow cells will then travel to the bone marrow space and begin growing and produce new blood cells.

  • Recovery and monitoring:

    After the bone marrow transplant surgery, the patient will need to remain hospitalized for several weeks to recover. During this time, he/she will be closely monitored for any signs of infection/complications. The patient will also need to take medications to prevent the rejection of new bone marrow cells.

  • Follow-up care:

    After leaving the hospital, the patient will need to undergo regular follow-ups with their healthcare team to observe and monitor the patient's progress and make any necessary adjustments to their treatment plan.

  • Methods/Techniques used for Performing Bone Marrow Transplant Procedure

  • Allogeneic Transplant

    This method involves the transfer of bone marrow from a healthy donor to the patient. The donor and the recipient must have a closely matched tissue type to reduce the risk of rejection. Before the transplant, the patient undergoes high-dose chemotherapy and/or radiation therapy so that the diseased bone marrow is destroyed. Once the diseased bone marrow is eradicated, the donor bone marrow is infused into the bloodstream where it migrates to the bones and eventually replaces the diseased marrow.

  • Autologous Transplant

    This method involves using the patient's own bone marrow. The patient's healthy bone marrow is harvested and stored before the high-dose chemotherapy and/or radiation therapy. After the therapy, the stored bone marrow is infused back into the patient's bloodstream where it migrates to the bones and replaces the diseased marrow.

  • Umbilical Cord Blood Transplant

    This method involves using umbilical cord blood from a healthy donor. Cord blood is collected and stored at the time of birth and stored until it is needed for the transplant. The donor and recipient do not need to have a closely matched tissue type. The procedure is similar to allogeneic transplant.

  • Post Procedure Details

  • Recovery

    After the transplant, the patient needs to remain hospitalized for several weeks to monitor for complications. He/She may experience side effects like nausea, vomiting, diarrhea, fatigue, and mouth sores. The patient's immune system is weakened, so they are at risk for infections. The patient may need to take antibiotics and antifungal medications to prevent infection.

  • Follow-up Care

    The patient will need to continue to see their healthcare provider for regular check-ups and blood tests to monitor their progress. The patient may need to take medications to prevent graft-versus-host disease, a condition where the donor's immune system attacks the recipient's body.

  • Long-term Effects

    The long-term effects of bone marrow transplant vary depending on the patient's age, overall health, and the type of transplant. Some patients may fully recover and return to their normal activities, while others may experience long-term complications such as infertility, cataracts, and an increased risk of developing certain types of cancer.

  • Risks and Complications Associated with Bone Marrow Transplant Surgery

  • Graft-Versus-Host Disease

    This is a common complication where the donor's immune system attacks the recipient's body. Symptoms may include rash, diarrhea, and liver problems.

  • Infection

    Patients can develop an infection due to the weakened immune system. Infections can be life-threatening.

  • Bleeding

    Patients may experience bleeding due to the destruction of platelets during the high-dose chemotherapy and/or radiation therapy.

  • Organ Damage

    Patients may experience damage to organs such as the liver, lungs, and kidneys due to the high-dose chemotherapy and/or radiation therapy.

  • Death

    In rare cases, patients may die due to complications associated with the transplant.

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    DisclaimerThe cost of bone marrow transplant depends on the following factors: the city, the hospital that is selected, the complexity of the procedure and the room chosen by the patient. The price range mentioned here is an approximation of the surgery cost; Bajaj Finserv Health does not claim that these prices are an exact estimate. For exact information about surgery charges, it is best inquire at the selected hospital.