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Agree toTerms and ConditionsPlasmapheresis is a medical procedure. This is done to remove and separate plasma from the blood. Plasma is the name of the liquid part of blood that contains various proteins, antibodies, and other important components. Plasmapheresis, also known as plasma exchange, is typically used to treat autoimmune disorders and other conditions that affect the immune system. This procedure is performed using a special machine that separates plasma from blood cells. The separated plasma is then replaced with a substitute solution, such as saline or albumin, and the blood cells are returned to the patient's body. Plasmapheresis is typically performed as an outpatient procedure and can take several hours to complete.
Therapeutic plasmapheresis is used to treat a variety of medical conditions, including autoimmune disorders, neurological disorders, and blood disorders. This procedure involves the removal as well as replacement of plasma from the patient's blood and is typically performed on an outpatient basis.
Donor plasmapheresis is a type of plasmapheresis procedure that is used to collect plasma from healthy donors. This plasma is then used to create blood products, such as immunoglobulin, that can be used to treat patients with immune deficiencies or other medical conditions.
Preoperative plasmapheresis is a type of plasmapheresis procedure that is performed prior to certain surgeries, such as kidney transplants. This procedure is used to remove antibodies from the patient's blood that could potentially cause the transplanted organ to be rejected.
This type of plasmapheresis procedure is used to treat conditions that affect the blood, such as sickle cell disease or thrombotic thrombocytopenic purpura. This involves the removal and replacement of plasma, as well as the removal of red and white blood cells and platelets.
Immunoadsorption plasmapheresis is a type of plasmapheresis procedure that is used to remove specific proteins or antibodies from the patient's blood. This is typically used to treat autoimmune disorders like multiple sclerosis or myasthenia gravis. Thus, plasmapheresis is a medical procedure used to treat various medical issues by removing and replacing plasma from the patient's blood. There are several different types of plasmapheresis procedures. It is done on an outpatient basis. If you are considering plasmapheresis as an option, discuss the possible risks and expected benefits of the procedure with your healthcare team.
Autoimmune disorders
Neurological disorders
Kidney diseases
Blood disorders
Liver diseases
The removal of plasma can help reduce the levels of harmful substances in blood like autoantibodies or toxins and improve overall health. In some cases, plasmapheresis may be used as a temporary treatment option while other treatments are being sought or as a long-term solution for chronic conditions.
Inform your doctor of any medications you are taking, including over-the-counter drugs, supplements, and herbal remedies. Some medications may need to be discontinued prior to the procedure.
Drink a lot of fluids in the days before the surgery to ensure proper hydration.
Avoid caffeine or alcohol for a minimum of 24 hours prior to the procedure.
Eat a light meal before the surgery to prevent nausea or dizziness during the procedure.
Dress in comfortable clothes that allow easy access to the arms, as the procedure involves inserting needles into the veins.
Arrange for a ride home after the procedure, as you may feel weak or dizzy. It is also important to discuss any small and big concern or question you may have with your doctor prior to the procedure to ensure you are fully informed and comfortable with the process.
Blood tests to check for kidney and liver function
Electrocardiogram (ECG) to evaluate heart function
Chest X-ray to evaluate lung function
Urinalysis to check for the presence of proteins in the urine
Additionally, the patient will need to discuss with the doctor their medical history and mention a list of medications they are currently taking. It is important to inform the healthcare provider of any known or suspected allergies or adverse reactions to medications.
During the plasmapheresis procedure, the patient is connected to a machine that removes blood from the body through a needle or catheter. The blood is then separated by the machine into various components, including plasma, red blood cells, and white blood cells. The plasma, which contains the antibodies causing the disease, is collected and discarded, while the remaining blood components are returned to the patient's body.
The patient is connected to the plasmapheresis machine, which consists of a blood pump and a plasma separator.
A needle/catheter is inserted into a vein in the arm or leg to allow blood to flow out of the body and into the machine.
The machine separates the blood into its components and removes the plasma, which is collected in a bag or container.
The remaining blood components are mixed with a replacement fluid, such as saline or albumin, before being returned to the patient's body through a separate needle or catheter.
The procedure usually takes between 1-3 hours, depending on the amount of plasma that needs to be removed.
After the procedure is complete, the patient is monitored for any adverse effects and may be given additional fluids to replace any lost during the procedure.
Plasmapheresis surgery may need to be repeated several times, depending on the patient's condition and response to treatment. It is crucial to carefully follow all post-operative instructions provided by the medical experts to ensure a successful recovery.
Centrifugation technique
Membrane filtration technique
Double filtration plasmapheresis technique
Immunoadsorption technique
Centrifugation technique involves separating plasma from blood cells using a centrifuge. The separated plasma is then replaced with a replacement fluid. Membrane filtration technique involves passing blood through a membrane filter, separating plasma from blood cells. The separated plasma is then replaced with a replacement fluid. Double filtration plasmapheresis technique involves passing blood through two membrane filters, separating plasma from blood cells and then filtering out unwanted substances. The separated plasma is then replaced with a replacement fluid. Immunoadsorption technique involves passing blood through a column containing an adsorbent material that selectively removes harmful substances from the plasma. The separated plasma is then replaced with a replacement fluid.
After the plasmapheresis procedure, the patient may experience some side effects like dizziness, fatigue, and nausea. These side effects usually subside within a few hours. The patient may also experience a decrease in blood pressure and an increase in heart rate during the procedure. The medical team will monitor the patient's vitals all throughout the procedure. The patient may be required to rest for a few hours after the procedure. They may also be advised to drink plenty of fluids to replace the lost plasma.
These can occur at the site where the needle is inserted.
There is a risk of infection at the site where the needle is inserted.
Plasmapheresis can cause a decrease in the blood pressure level, potentially leading to dizziness or fainting.
Removing large amounts of plasma can cause fluid imbalance in the body, which can lead to dehydration.
Some patients may get an allergic reaction to the replacement fluid used during the procedure.
Blood clotting may occur during the procedure, which can lead to a blockage in the blood vessels.